Partners/Collaborators

Strategic Alliances

AbbVie

In June 2010, Neurocrine Biosciences entered into an exclusive worldwide collaboration with AbbVie (formerly Abbott) to develop and commercialize elagolix for women’s and men’s health. Under the terms of the agreement with AbbVie, AbbVie is responsible for future development and commercialization. In 2018, AbbVie received approval for ORILISSA® (elagolix) to treat pain associated with endometriosis. AbbVie is responsible for all development, marketing and commercialization costs and Neurocrine Biosciences is entitled to a royalty on worldwide sales of ORILISSA and elagolix.

Mitsubishi Tanabe Pharma

In March 2015, Neurocrine Biosciences entered into an exclusive collaboration and licensing agreement with Mitsubishi Tanabe Pharma Corporation for the development and commercialization of valbenazine for movement disorders in Japan and other select Asian markets.

Mitsubishi Tanabe will be responsible for all development, marketing and commercialization costs in their territories and Neurocrine Biosciences will be entitled to a percentage of sales by Mitsubishi Tanabe. Neurocrine Biosciences retains full commercial rights to valbenazine in North America, Europe and other countries outside of Asia.

BIAL

On February 9, 2017, Neurocrine Biosciences entered into an exclusive licensing agreement with BIAL for the development and commercialization of opicapone in the United States and Canada. Opicapone is a once-daily, peripherally-acting, selective COMT inhibitor that was approved in June 2016 by the European Commission as an adjunct therapy for adult patients with Parkinson’s disease. Neurocrine Biosciences is responsible for the management and cost of all opicapone development and commercialization activities in the United States and Canada. The Company is in the process of preparing for a New Drug Application (NDA) submission which it anticipates will occur during the second quarter of 2019.

JNANA THERAPEUTICS

On October 9, 2018, Neurocrine Biosciences entered into a research collaboration with Jnana Therapeutics aimed at discovering novel small molecule therapeutics for multiple targets for central nervous system (CNS) disorders.

VOYAGER THERAPEUTICS

On January 29, 2019, Neurocrine Biosciences entered into a strategic collaboration with Voyager Therapeutics focused on the development and commercialization of Voyager’s gene therapy programs, VY-AADC for Parkinson’s disease and VY-FXN01 for Friedreich’s ataxia, as well as rights to two programs to be determined.