Partners/Collaborators

Strategic Alliances

AbbVie

In June 2010, Neurocrine Biosciences entered into an exclusive worldwide collaboration with AbbVie (formerly Abbott) to develop and commercialize elagolix for women’s health. Under the terms of the agreement, AbbVie is responsible for future development and commercialization.

In 2018, AbbVie received U.S. FDA approval for ORILISSA® (elagolix) to treat pain associated with endometriosis. In 2020, AbbVie received U.S. FDA approval for ORIAHNN™ (elagolix, estradiol, and norethindrone acetate capsules; elagolix capsules) to manage heavy menstrual bleeding associated with uterine fibroids in pre-menopausal women. Under the collaboration, elagolix is also being investigated for the treatment of polycystic ovary syndrome. AbbVie is responsible for all development, marketing and commercialization costs and Neurocrine Biosciences is entitled to a royalty on worldwide sales of ORILISSA, ORIAHNN and any other product containing elagolix.

Mitsubishi Tanabe Pharma

In March 2015, Neurocrine Biosciences entered into an exclusive collaboration and licensing agreement with Mitsubishi Tanabe Pharma Corporation for the development and commercialization of valbenazine for movement disorders in Japan and other select Asian markets.

Mitsubishi Tanabe will be responsible for all development, marketing and commercialization costs in their territories and Neurocrine Biosciences will be entitled to a percentage of sales by Mitsubishi Tanabe. Neurocrine Biosciences retains full commercial rights to valbenazine in North America, Europe and other countries outside of Asia.

BIAL

Neurocrine Biosciences acquired the exclusive U.S. and Canadian rights to ONGENTYS® (opicapone) from Portela & CA, S.A. (BIAL) in 2017. In April 2020, ONGENTYS was approved by the U.S. Food and Drug Administration (FDA) as an add-on treatment to levodopa/carbidopa in patients with Parkinson’s disease experiencing “off” episodes.

JNANA THERAPEUTICS

On October 9, 2018, Neurocrine Biosciences entered into a research collaboration with Jnana Therapeutics aimed at discovering novel small molecule therapeutics for multiple targets for central nervous system (CNS) disorders.

VOYAGER THERAPEUTICS

On January 29, 2019, Neurocrine Biosciences entered into a strategic collaboration with Voyager Therapeutics focused on the development and commercialization of Voyager’s gene therapy programs, NBIb-1817 for Parkinson’s disease and VY-FXN01 for Friedreich’s ataxia, as well as rights to two programs to be determined.